How Vitamin E interacts with Anticoagulant medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Vitamin E may increase the bleeding effect of these medications when taken in high doses. Vitamin E can also increase blood clotting time. Therefore, taking high doses of this vitamin is not advised for individuals taking anticoagulant drugs. Use with caution. (1)

These drugs include warfarin, heparin, dalteparin, tinzaparin, enoxaparin, danaparoid sodium, antithrombin III, lipirudin, argatroban, bivalirudin,


  1. View Abstract: Corrigan JJ Jr, et al. Effect of Vitamin E on Prothrombin Levels in Warfarin-induced Vitamin K Deficiency. Am J Clin Nutr. Sep1981;34(9):1701-05.