How Eicosapentaenoic Acid (EPA) interacts with olestra

Interaction type: Interactions

Interaction rating: Potential/Theoritical

The non-fat, calorie-free cooking oil decreases the absorption of fat-soluble nutrients, such as EPA, from the digestive tract. Supplementation with the affected nutrient may be necessary. (1)


  1. View Abstract: Thomson AB, Hunt RH, Zorich NL. Review Article: Olestra and Its Gastrointestinal Safety. Aliment Pharmacol Ther. Dec1998;12(12):1185-200.