How Coenzyme Q10 (CO-Q10) interacts with Beta-blockers

Interaction type: Depletions

Interaction rating: Study Supported

Many of the members of this class of drugs have been reported to inhibit enzymes necessary for the synthesis of coenzyme-Q10. Supplementation with the affected nutrient may be necessary. (1)

These drugs include atenolol, esmolol, betaxolol, penbutolol, carteolol, bisoprolol, pindolol, metoprolol, timolol, sotalol, acebutolol, nadolol, propranolol, labetalol, carvedilol, levobunolol, levobetaxolol, metipranolol


  1. View Abstract: Kishi T, et al. Bioenergetics in Clinical Medicine XV. Inhibition of Coenzyme Q10-enzymes by Clincically used Adrenergic Blockers of Beta-receptors. Res Commun Chem Pathol Pharmacol. May1977;17(1):157-64.