How Beta-Carotene interacts with mineral oil

Interaction type: Depletions

Interaction rating: Potential/Theoritical

Fat-soluble nutrients including beta-carotene dissolve in mineral oil, which reduces their absorption and increases their excretion. If extended use of this agent is warranted, supplementation with the affected nutrient(s) may be necessary. (1)


  1. Diarrhea and Constipation. In: Berkow R, Fletcher AJ, Beers MH, et al, eds. The Merck Manual of Diagnosis and Therapy. 16th ed. Rahway, NJ: Merck Research Laboratories; 1992:810.