CoQ10 may help lower blood pressure in Type 2 diabetes.




Eur J Clin Nutr.

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Consumer Data: Coenzyme Q10 (CO-Q10) Diabetes Mellitus, Type 2
Professional Data: Coenzyme Q10 (CO-Q10) Diabetes Mellitus, Type 2


Coenzyme Q10 is an important, vitamin-like compound that is present throughout the body. While there are 10 other coenzyme Q compounds present in nature, coenzyme Q10 is the only one present in humans. Although coenzyme Q10 is widely used throughout Europe and Asia, its value is just beginning to be recognized in the United States for its support of cardiovascular health and more.

Coenzyme Q10's benefits are due to the following two attributes. First, Co-Q10 is an important fat-soluble antioxidant that is uniquely able to protect the cells' energy producing machinery, known as mitochondria, from free radical damage. Second, coenzyme Q10 is necessary for the production of energy in all cells of the body. Even though coenzyme Q10 occurs in the cells of all plants and animals, dietary sources do not provide adequate levels of this nutrient.

Researchers wanted to investigate the role of CoQ10 supplementation in Type 2 diabetes. Their objective was to see the effects this supplement could have on glycemic control as well as blood pressure. Seventy-four hypertensive diabetics were recruited for a 12-week study. This double blind placebo controlled study administered 100 mg CoQ10 twice a day, 200 mg of fenofibrate once daily, both, or neither to the subjects. The results showed that fenofibrate did not alter blood pressure while the CoQ10 lowered the diastolic and systolic blood pressure. The authors concluded that, " These results show that CoQ supplementation may improve blood pressure and long-term glycemic control in subjects with type 2 diabetes."1


1. Hodgson JM, et al. Coenzyme Q10 imporves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. Nov 2002;56:1137-1142.