Composition and antituberculosis activity of the volatile oil of Heliotropium indicum Linn. growing in Phitsanulok, Thailand.

Author

Machan, T.

Date

2005

Journal

Flavour and Fragrance Journal

The volatile oil from the aerial parts of H. indicum was isolated by hydrodistillation and analysed by a combination of gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The essential oil was obtained in 0.004% yield as a light brown liquid. The major constituents of the volatile oil of H. indicum were phytol (49.1%), 1-dodecanol (6.4%) and ?-linalool (3.0%). In addition, the volatile oil showed significant antituberculosis activity against Mycobacterium tuberculosis H37Ra in the Alamar blue assay system with an MIC of 20.8 ?g/ml.