Chemical Constituents and Antimicrobial Activities of Goniothalamus sp.


Azah M.A., Mastura M., Mailina J., Abu Said., Mohd Faridz, Z.P., Nik Yasmin N.Y. & Ahmad Abdul Qayyum M.,  Medicinal Plants Programme, Forest Biotechnology Division, Forest Institut Malaysia, 52109 Kepong, Selangor.  Tel:  03-62797362   Email: sitihumeirah@frim   Puad M.A., 7 Masturah, Muhajir, H.




Chemical Constituents and Antimicrobial Activities of Goniothalamus sp.


Medicinal and Aromatic Plants Seminar (MAPS 2008)


21st October - 22nd October 2008

Place Held

The Legend Hotel, Kuala Lumpur


The aerial parts of Goniothalamus macrophyllus and Goniothalamus tortilipetalus were collected from Pasoh Forest Reserve and subjetced by hydro distillations for 8 hours. Essential oils obtained were analyzed by GC and GC/MS analytical methods. The results showed that the oils possess the following major compound: G. macrophyllus: twig; geranyl acetate (45.5%), linalool (12.7%) and geraniol (17.0%), root ; cyperene (9.8%), geranyl acetate (9.4%) and camphene (7.5%) and G. tortilipetalus: leaves; O-cymene (43.0%), piperitone (11.5%) and 1,8-cineole (5.8%). Antimicrobial activities of all the oils were evaluated against eleven microorganisms including MRSA Staphylococcus aureus, gram positive bacteria, gram negative bacteria and dermatophyte fungi using single concentration test and broth micro dilution methods. All of the oils inhibited the growth of test microorganism studies except for Pseudomonas aeruginosa (gram negative bacteria). The gram positive bacteria is more sensitive than gram negative and fungus. The antimicrobial activity could be due to presence of geraniol and linalool which have been reported to have significant activities.


Goniothalamus macrophyllus; Goniothalamus tortilipetalu; essential oils composition; antimicrobial activity


Plenary: Session 3


Think Global, Act Local: A New Paradigm In Malaysian Herbal Industry (Prof. Emeritus Dr. Abdul Latif Ibrahim-UNISEL)