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Flemingia strobilifera

Synonyms

Flemingia fruticulosa, Moghania fruticulosaMoghania bracteataHedysarum strobiliferum, Zornia strobilifera 

Vernacular Names:

Malaysia

Seringan, Meringan

English Luck Plant, Wild Hops
China Qui Sui Qian Jin Ba
Vietnam Top Mo Bong Tron, Duoi Chon, Top Mo Co Choi, Dau Ma Hoa Non
Philippines Kupies, Kopkopies (Ilocano); Adoteid, Gangan, Kaliakai, Kopa-kopa, Kupau-kupau, Pakayan, Panapanalahan, Panapnarahan, Paking, Payang-payang Na Babae, Payang-payang, Piragan, Tabang-bayawak
Palauan Besungelaiei, Pesungel a iei
India Kusrunt (Oudh); Simbusak (Santal); Bundar, Kanaphuti (Bombay)
Sri Lanka Ham-pinna
Nepal Grop Muja, Jyugar, Ghari Mamarkha, Jogbiro (Chepang); Barkuali Jhar, Chunetro Ghans, Duware, Gahate, Sangle Jhar, Swata, Syano Bbatyaula (Nepali); Batya (Raute); Gahate, Mranche (Tamang)
French Sainfoin du Bengale [2]

General Information

Description

Flemingia strobilifera is a shrub of the Fabaceae family. It grows up to 1m high. It has numerous branches, rodded, villous and covered by minute resinous granular globules, at first white but later turning red. The leaves are somewhat deflexed, subovately oblong with a short point measuring 5-15cm x 2-4cm. The nerves are parallel, straight, many, hairy underneath. The base is cordate. The petiole is several times shorted than the leaf, villous, straight, ascending, with a thickened flexile joint at each end. The stipules are caducous. Racemes compound; racemules enclosed in large leafy imbricated bracts. The flowers are dull greenish dirty white, small. The corolla is not much longer than the calyx: standard broad, reflex, streaked. The wings shorter than the vexillum, narrow. The keel longer than the wings, the two petals running into one towards the upper part of the underside. The stamens diadelphous. The germen pedicled, elliptical, flattened, shaggy, two-seeded; ovules kidney-shaped. The style several times longer, slender, from a thicker middle tapering towards each end. The stigma headed, pale.

Plant Part Used

Leaves, Barks and Roots [2-4]

Chemical Constituents

5,7,4’-trihydroxy-8,2’,5’-tri(3-methylbut-2-enyl)isoflavone; 5,7,2’,4’-tetrahydroxyisoflavone; 5,7,4’-trihydroxyisoflavone; b-sitosterol;

Traditional Used:

Gastrointestinal Disaease

The Nepalese [1] recognised this plant as useful in the treatment of various gastrointestinal complaints. For indigestions they prescibed the paste of the roots in the dose of 2 teaspoons twice a day. Juice of the roots is given for diarrhoea and dysentery, so it the juice of the bark.

Inflammatory Diseases

It is widely used to treat rheumatism in India and Southeast Asia. It has been advocated in the treatment of fever. In Nepals [1] the juice of the bark is given in the dose of four teaspoons twice daily. In Malaysia [2] fever is contained by bathing the patient with a decoction of the leaves. To treat cases of tuberculosis the Filipinos make use of the decoction of the leaves and flowers.

Central Nervous System Diseases

The roots of the plant is known to have sedating properties (as indicated by the Malaysian name Meringan – meaning to lighten). It is being used to contained hyperactive children and induce sleeping at night. In Perak the leaves and flowers used to be stuffed into pillows to provided this effects. The roots are used to treat epilepsy and hysteria.[2][4][5]

Obstetrics & Gynaecology

In the immediate post partum period the people of India and the Malay Archipelago made use of the leaves either singly or in combination with others in a decoction to bathe the mothers. The purpose is to provide a sense of calmness following the tiring and agonizing journey of labour. [2][3]

Other uses

In Trinidad and Tobago where this plant was introduced in the early 16th century the traditional medical practitioner had recogized its usefullness in treating kidney problems especially kidney stones.[3] In Java the leaves are given to children as vermifuge. The plant extract is applied over ringworms three times daily as a remedy for this disfiguring skin disease. [3][6]

Pre-Clinical Data

Pharmacology

Antibacterial acitivity

A number of isoflavone isolated from the roots of F. strobilifera showed moderated antibactierial activity an anti-oxidant activtiy.[7] In a screening exercise of the antibacterial properties of the roots it was found that the root juice extract was able to inhibit the growth of Staphylococcus aureus and Escherichia coli.[8]

Gastro-protective activity

The chloroform extract of the roots was a subject of scrutiny for its gastro-protective activity. Studies found that giving the chloroform extracts in a dose of 15mg/kg and 20mg/kg could reduce the ulcer indices significantly in rats with indomethacin induced ulcers. [9]

Toxicities

No documentation

Clinical Data

Clinical Trials

No documentation

Adverse Effects in Human:

No documentation

Used in Certain Conditions

Pregnancy / Breastfeeding

No documentation

Age Limitations

Neonates / Adolescents

No documentation

Geriatrics

No documentation

Chronic Disease Conditions

No documentation

Interactions

Interactions with drugs

No documentation

Interactions with Other Herbs / Herbal Constituents

No documentation

Contraindications

Contraindications

No documentation

Case Reports

No documentation

References

    1. N. P. Manandhar, Sanjay Manandhar  Plants and people of Nepal Timber Press Portland 2002pg 237
    2. Timothy Johnson  CRC ethnobotany desk reference CRC Press Boca Raton 1999 pg. 352
    3. Philippines Medicinal Plants (http://www.stuartxchange.org/Panapanarahan.html) Accessed date: 26th June 2010)
    4. K. M. Nadkarni  Dr. K. M. Nadkarni's Indian materia medica: Repr, Volume 1 Popular Prakashan Pvt. Ltd Mumbai 1976  pg556
    5. Dr. V. Singh & Dr. D.K. Jain  Taxonomy of Angiosperms Rastogi Publication New Delhi 2005 pg. 255
    6. Ethel Kullmann Allen  The Leguminosae, a source book of characteristics, uses, and nodulation University of Wisconsin Press Madison 1981 pg. 288
    7. Swati Madan,  Gynandra Nath Singh, Kanchan Kohli, Mohamed Ali, Tatendra Kumar, Raman Mohan Singh and Om Prakash Isoflavonoids from Flemingia Strobilifera (L.) R.Br. Roots  Acta Poloniae Pharmaceutica – Drug Research 2009 Vol 66(3):297-303
    8. R.B. Mahato and R.P. Chaudhary Ethnomedicial Study and Antibacterial Activities of Selected Plants of the Palpa District, Nepal.Scientific World 2005 Volume 3(3): 26-31
    9. K.V. Anil Kumar, Babul Dewan, T. Rama Evaluation of Gastro-protective effects of Flemingia strobilifera (L) R. Br. (Fabaceae) Root Extract. Arch Pharm Sci & Res April 2010 Vol. 2(2):347-353

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